The National Drug-Related Deaths Index also shows that prescription drugs continue to account for the greatest amount of poisonings.
The index, compiled by the Health Research Board, shows that a total of 695 deaths were caused by drugs in 2015, or almost two people per day.
Down from 719 in 2014 (the highest on record), it comprised 348 poisonings (overdoses) and 347 non-poisoning deaths.
The latter comprises of 156 trauma fatalities, such as suicides, and 191 medical deaths, such as cardiac events.
Source: Cormac O'Keffee, The Irish Examiner, 12/12/17